The screening program is directed to research institutions from Poland and Norway, and compounds will be tested free of charge.
In the Project we focus on two main molecular targets which are recognized as important in antidepressant/anxiolytic mechanism of action:
the serotonergic system – compounds with dual SERT/5-HT1A antagonistic activity, and ligands of 5-HT6 and 5-HT7 receptors;
the glutamatergic system – in which we are mainly concentrated on groups II and III of metabotropic glutamate receptors (mGluR).
The chemical structures of the submitted compounds are regarded as an intellectual property of a Participant and will be protected as stated in the General Principles of Co-operation
(Polish version).
For more information please contact: Andrzej Bojarski
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